Chromosome localization of two human serine protease genes to region 14q11.2→q12 by in situ hybridization

摘要

Two human serine protease genes have been cloned. One corresponds to CTLAl, the human equivalent of the mouse cytotoxic cell protease gene Ctla-1, and the other is novel. Both genes were localized to 14q 11.2→q 12 by in situ hybridization. This result confirms the assignment of human CTLAl to 14q11.2→q12 and provides new mapping data for another human serine protease gene located in the same chromosome reg