Disseminated Cutaneous and SynovialMycobacterium marinumInfection in a Patient With Systemic Lupus Erythematosus

摘要

INFECTION is often cited as the primary cause of death in patients with systemic lupus erythematosus (SLE), commonly due to gram-negative bacteria, fungi, and other opportunistic organisms. The prevalence of tuberculosis associated with SLE has been reported to be as high as 5%, whereas atypical mycobacterial infection has been reported only occasionally.Mycobacterium marinum is an atypical mycobacterium first isolated from salt-water fish and reported to cause granulomatous skin lesions in swimmers. Disseminated disease is uncommon and is usually seen only in immunocompromised hosts.We report the first case of late disseminated cutaneous and synovialM marinuminfection in a patient with active SLE.