Synthesis Of The Hamigerans. A Review

摘要

In a long series of publications,Cambie and his colleagues have described numerous natural products isolated from marine sponges.Part 19 of the series is especially noteworthy since it reports the structures of a group of compounds that includes a substance - hamigeran B(1)- which shows very impressive activity against polio and herpes viruses.The compounds were isolated from a marine sponge collected in shallow water off the north east coast of New Zealand.A total of eight compounds were obtained from the sponge;they have the structures 1-8 shown in Scheme 1.