Myostatin inhibition promotes fast fibre hypertrophy but causes loss of AMP-activated protein kinase signalling and poor exercise tolerance in a model of limb-girdle muscular dystrophy R1/2A

Kramerova Irina; Marinov Masha; Owens JaneLee Se-JinBecerra DianaSpencer Melissa J.

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Myostatin inhibition promotes fast fibre hypertrophy but causes loss of AMP-activated protein kinase signalling and poor exercise tolerance in a model of limb-girdle muscular dystrophy R1/2A

机译：Myostatin inhibition promotes fast fibre hypertrophy but causes loss of AMP-activated protein kinase signalling and poor exercise tolerance in a model of limb-girdle muscular dystrophy R1/2A

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来源
《The Journal of Physiology》 |2020年第18期|3927-3939|共13页
作者
Kramerova Irina; Marinov Masha; Owens JaneLee Se-JinBecerra DianaSpencer Melissa J.;
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作者单位

Univ Calif Los Angeles, David Geffen Sch Med, Dept Neurol, Los Angeles, CA 90095 USA;

Pfizer Inc, Cambridge, MA USA;

Jackson Lab, Farmington, CT USA;

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原文格式 PDF
正文语种英语
中图分类人体生理学;
关键词
calpain; muscular dystrophy; myostatin; skeletal muscle;

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Myostatin inhibition promotes fast fibre hypertrophy but causes loss of AMP-activated protein kinase signalling and poor exercise tolerance in a model of limb-girdle muscular dystrophy R1/2A

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