One-Pot Synthesis of Selected P-Vinylbenzyls under Solvent-Free Conditions

摘要

One-pot synthesis of selected P-vinylbenzyls under solvent-free conditions was elaborated on a multigram scale. Several techniques have been used to characterize properties of all new products: MS, HRMS, E.A., and multinuclear NMR in solution and solid-state. The structure of 5,5-dimethyl-2-(4-vinylbenzyl)-1,3,2-dioxaphosphinane 2-oxide (2 d) was determined by single-crystal X-ray diffraction measurements rationalized based on DFT calculation. The X-ray and NMR studies of 2 d indicate the appearance of an anomeric effect.