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Deep Brain Stimulation for Substance Use Disorders? An Exploratory Qualitative Study of Perspectives of People Currently in Treatment

机译:物质使用障碍的深部脑刺激?对目前正在接受治疗的人的观点的探索性定性研究

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ObjectiveAlthough previous studies have discussed the promise of deep brain stimulation (DBS) as a possible treatment for substance use disorders (SUDs) and collected researcher perspectives on possible ethical issues surrounding it, none have consulted people with SUDs themselves. We addressed this gap by interviewing people with SUDs.MethodsParticipants viewed a short video introducing DBS, followed by a 1.5-hour semistructured interview on their experiences with SUDs and their perspective on DBS as a possible treatment option. Interviews were analyzed by multiple coders who iteratively identified salient themes.ResultsWe interviewed 20 people in 12-step-based, inpatient treatment programs (10 50 White/Caucasian, 7 Black/African American 35, 2 Asian 10, 1 Hispanic/Latino 5, and 1 5 Alaska Native/American Indian; 9 women 45, 11 men 55). Interviewees described a variety of barriers they currently faced through the course of their disease that mirrored barriers often associated with DBS (stigma, invasiveness, maintenance burdens, privacy risks) and thus made them more open to the possibility of DBS as a future treatment option.ConclusionsIndividuals with SUDs gave relatively less weight to surgical risks and clinical burdens associated with DBS than previous surveys of provider attitudes anticipated. These differences derived largely from their experiences living with an often-fatal disease and encountering limitations of current treatment options. These findings support the study of DBS as a treatment option for SUDs, with extensive input from people with SUDs and advocates.
机译:目的尽管先前的研究已经讨论了深部脑刺激 (DBS) 作为物质使用障碍 (SUD) 的可能治疗方法的前景,并收集了研究人员对其可能存在的伦理问题的看法,但没有一项研究咨询过 SUD 患者本身。方法参与者观看了一段介绍DBS的简短视频,然后进行了1.5小时的半结构化访谈,介绍了他们使用SUD的经历以及他们对DBS作为可能的治疗选择的看法。多位编码人员对访谈进行了分析,他们反复确定了突出的主题。结果我们在基于12个步骤的住院治疗项目中采访了20人(10名[50%]白人/白种人,7名黑人/非裔美国人[35%],2名亚裔[10%],1名西班牙裔/拉丁裔[5%]和1名[5%]阿拉斯加原住民/美洲印第安人;9名女性[45%],11名男性[55%])。受访者描述了他们目前在疾病过程中面临的各种障碍,这些障碍反映了通常与DBS相关的障碍(耻辱感,侵入性,维护负担,隐私风险),从而使他们对DBS作为未来治疗选择的可能性更加开放。结论与之前对提供者态度的调查相比,SUDs患者对与DBS相关的手术风险和临床负担的重视程度相对较低。这些差异很大程度上源于他们患有一种通常致命的疾病的经历,并遇到了当前治疗方案的局限性。这些发现支持了 DBS 作为 SUD 治疗选择的研究,并得到了 SUD 患者和倡导者的广泛投入。

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