Antral gastrin cell hyperfunction in children

摘要

Objective:A description of the clinical history, diagnosis and management of a child with antral gastrin cell hyperfunction.Design:Detailed studies of hormonal, endoscopic and morphologic patterns.Setting:Gastrointestinal endocrinology section of a university hospital.Patient:A 14-year-old boy who complained of two episodes of acute upper gastrointestinal bleeding due to duodenal ulcer.Interventions and outcome measures:H2-antagonist therapy.Conclusions:Antral gastrin cell hyperfunction can be an underlying cause of peptic ulcer in children. The diagnosis is made by basal and protein meal-stimulated serum gastrin levels. Long-term H2-antagonist treatment is suggested.