Synthesis of New Fused Derivatives of 4-(Fur-2-yl)pyrano4,3-bpyridines

摘要

A method for the synthesis of new fused derivatives of 4-(fur-2-yl)pyrano[4,3-b]pyridines was developed by hydrolysis of 2-chloro-4-(2-furyl)-7,7-dimethyl-7,8-dihydro-5H-pyrano[4,3-b]pyridine-3-carbonitrile, its further reaction with hydrazine hydrate and thioglycolic acid. The direction of electrophilic substitution in the pyridine ring was studied.