In a prospective, multicenter cohort trial of intubated patients with COVID-19, 27.7% were identified as having pulmonary aspergillosis using a definition based on influenza. While invasive pulmonary aspergillosis (PA) is usually seen among patients with highly suppressed immune systems, it has been recently recognized in those with influenza, and now in those with COVID-19. Presentation of PA as a complication of these viral infections appears to be distinct. New diagnostic rules have been developed.
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