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The effect of epidermal pigmentation on selective vascular effects of pulsed laser

机译:表皮色素沉着对脉冲激光选择性血管效应的影响

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AbstractThe effect of epidermal pigmentation on the threshold exposure dose for inducing purpura with a tunable dye laser at 577 nm, 1.5 μs pulse duration, was studied in 21 human volunteers with varied genetically determined amounts of melanin. More laser energy was required to produce purpura as constitutive skin pigmentation increased. Histology showed that, in lighter skin, the laser threshold dose produced the most specific vascular injury with no disruption of surrounding structures. In more pigmented skin, damage occurred in the epidermal basal layer and very few changes were seen in blood vessels below
机译:摘要 以21名具有不同基因决定的黑色素含量的人类志愿者为研究对象,研究表皮色素沉着对诱导紫癜的577 nm、1.5 μs脉冲持续时间的可调谐染料激光诱导紫癜阈值暴露剂量的影响。随着组成型皮肤色素沉着的增加,产生紫癜需要更多的激光能量。组织学表明,在较浅的皮肤中,激光阈值剂量产生最特异性的血管损伤,而不会破坏周围结构。在色素沉着较多的皮肤中,表皮基底层发生损伤,下面的血管几乎没有变化

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