The Natural History of‘Focal Cerebral Vascular Disease’

摘要

The natural history of 500 patients was studied prospectively over a mean period of 4.6 years (S.D. 2.8).One hundred and fifty-one patients presented with cerebral vascular insufficiency and of these 94 developed a stroke later in the history.Three hundred and forty-nine patients presented with a stroke and of these 164 had no further stroke episode. One hundred and eighty-five had further stroke episodes and in 76.8 per cent this occurred within three years of the onset of the disease.The worst prognosis was associated with recurrent stroke episodes as indicated by the survival rates. The survival rates for transient vascular insufficiency uncomplicated by stroke were similar to those of the normal population.