AbstractThirteen sinus node arteries from human material (2 months post partum to 68 years) were studied by various histologic techniques for connective tissue, muscle, and nerve distribution and arrangement. Its relationship to the sinus node is also emphasized. The outer longitudinal muscle coat of the artery is replaced with a thick adventitia. This loss of smooth muscle is not typically found in other coronary arteries. In addition, many nerve fibers, arranged both circularly and longitudinally, present the possibility of a pressoreceptor mechanism related not only to coronary blood pressure changes but also to the neurogenic control of the heart beat.
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