Proteins Cells at Interfaces SIG

摘要

Mechanical forces play an essential role in various cellular processes, including cell spreading, migration and differentiation. The mechanical forces influence cell functions through mechanotransduction, or the conversion of mechanical forces into biochemical information by cells.1 This is a developmentally significant process, as cells respond to their environments as they are dynamically changing during development. Additionally, tissues in the body maintain mechanical homeostasis, or active remodeling to maintain consistent tissue properties. Disregulation of mechanical homeostasis is manifested in aging and disease. Mechanotransduction and mechanical homeostasis are some of the topics studied in the field of mechanobiology, or understanding how forces impact cellular processes, using tools developed to measure forces at the cell-matrix interface.