Selective Synthesis of Fluorine-Containing Enaminones of Benzofuran Series

摘要

Selective synthesis of regioisomers of fluorine-containing enaminones of the benzofuran series was carried out from benzofuranoyltrifluoroacetone according to a two-stage scheme. The possibility of targeted preparation of regioisomers, which were evaluated as Eu3+ complexones in aqueous solutions by the luminescence spectral method, was revealed in order to identify the prospects for their use in immunofluorescence analysis. The obtained enaminones form complexes with Eu3+ in aqueous solutions, however, over time, these complexes are hydrolyzed that was detected by the change of spectral characteristics through time.