Gestational trophoblastic disease (GTD) is a unique group of lesions because it is derived from the conceptus rather than from the patient. GTD is composed of a spectrum of interrelated disorders that can be broadly divided into three groups1: i) benign trophoblastic lesions (pla-cental site nodule and exaggerated placental reaction), which are nonneoplastic lesions and are usually incidental findings; ii) hydatidiform moles (complete, partial, and invasive moles), which are aberrant placental derivatives; and iii) gestational trophoblastic neoplasia (GTN) (choriocarcinoma, placental site trophoblastic tumor, and epithelioid trophoblastic tumor), some of which develop from their precursor lesions, ie, complete hydatidiform moles. Choriocarcinoma is the most common type of GTN#
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