Electrochemical Oxidation Involving Sulfonyl Hydrazine for the Synthesis of 2-Sulfonyl Quinolines/Pyridines

摘要

A mild electrochemical method was developed for the direct C2 sulfonylation of heteroaromatic N-oxides with sulfonyl hydrazides to obtain a serial of 2-sulfonyl quinoline/pyridine derivatives.The method has simple conditions,using potassium carbonate as base,CH3CN/H2O(9:1)as solvent,and reacting for 3 h under 15 mA current to prepare expected products.