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Strategies of airway management for head and neck photo-dynamic therapy

机译:头部和颈部的气道管理的策略photo-dynamic疗法

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Introduction Photodynamic therapy (PDT) is a minimally invasive treatment modality which has great clinical implications, especially in head and neck oncology. Post-operative swelling is a well-documented consequence of PDT. It is paramount the airway remains patent for these patients. A tracheostomy remains the gold standard treatment modality for base of tongue tumours susceptible to post operative PDT inflammation, which can lead to a compromised airway. We have carried out a retrospective study to outline the airway management strategies employed for head and neck cancer patients treated with PDT and suggest recommendations for future management. Materials and Methods This retrospective clinical study utilises 88 patients (53 males and 35 females) treated at the UCLH Head and Neck Center, London (between 2006 and 2013), for treatment of various lesions with superficial and/or interstitial PDT, when the airway could potentially be compromised. Results Of the 88 patients selected 60 had interstitial PDT (iPDT) and 13 had superficial PDT (sPDT). Fifteen patients were treated with both iPDT and sPDT. Among the iPDT patients 19 had a trachestomy; two patients a Quicktrach; four a Cook Airway Exchange Catheter (CEAC); one a percutaneous tracheostomy; one a needle tracheostomy and 33 patients did not receive any temporary airway pathways. Among the sPDT patients two had a trachestomy. Although the majority of patients did not suffer any major incidents, one sPDT patient required an emergency tracheostomy two days post-operatively. Conclusion Airway management is vital when planning PDT treatment for tongue based tumours. Consider a more conventional approach when the lesion being targeted is located at a higher risk site: Floor of mouth/posterior tongue/tongue base or when multiple oral sites are being treated. Lasers Surg. Med. 45:370-376, 2013.
机译:介绍光动力疗法(PDT)是一个微创的治疗方式伟大的临床意义,特别是在头和颈部肿瘤。证据确凿的PDT的结果。派拉蒙的气道仍然是这些专利病人。标准治疗模式为基础的舌头肿瘤术后PDT炎症,从而导致一个妥协气道。大纲气道管理策略用于头部和颈部癌症患者PDT治疗并且提出建议未来的管理。回顾性临床研究利用88个病人(53岁男性和35岁女性)UCLH治疗头部和颈部中心,伦敦(2006年之间2013),各种病变的治疗表面和/或间质PDT,当气道可能会受到损害。的88名患者选择60间质PDT (iPDT)和13个肤浅的PDT(领域)。15个病人iPDT和接受治疗领域。trachestomy;库克呼吸道交换导管(CEAC);经皮气管造口术;气管造口患者和33没有收到任何临时气管通路。患者两个trachestomy。大多数患者没有遭受任何专业事件,一个领域病人需要紧急气管造口手术后两天。结论气道管理是至关重要的基于规划PDT治疗舌肿瘤。当考虑一个更传统的方法损伤目标位于一个更高的风险网站:楼口/后舌头舌头基地或者当多个口腔站点正在接受治疗。激光Surg.地中海45:370 - 376,2013。

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