Comment: Tackling shared genetic underpinnings of migraine and ischemic stroke

摘要

In this large collaborative effort, Malik et al.(1) explore shared genetic variation underlying 2 common conditions: migraine and ischemic stroke (IS). Numerous studies have shown an increased risk of stroke in patients with migraine, but the contribution of genetic factors to this relationship is unclear.(2) The authors used the 2 largest existing meta-analyses of genome-wide association studies (GWAS) for both phenotypes.