What's new in shock, August 2010?

摘要

The study by Nin et al. (1) involves more than 12 medical institutions worldwide and deals with patients on ventilators who experience small increases (30%-50%) in serum crea-tinine in the course of ventilatory treatment. When these individuals were followed over time, such serum changes (increases in creatinine) seemed to be predictive of higher mortality, although the reasons for this association are not understood. Kapoor et al. (2) report that activation of the peroxisome proliferator-activated beta/delta receptor, using synthetic ligands specific for the receptor, attenuated the extent of ischemia/reperfusion injury in the rat heart.