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Type 2 diabetes and coronary artery disease: Preserved ejection fraction and sudden cardiac death

机译:2型糖尿病和冠心病:保存射血分数和突发性心脏病死亡

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BackgroundPrevious studies have shown that type 2 diabetes (DM2) is associated with sudden cardiac death (SCD) risk in post–myocardial infarction patients. The treatment of coronary artery disease (CAD) as well as DM2 has changed over time. ObjectiveThe purpose of this study was to compare the incidence of SCD in DM2 and nondiabetic patients with CAD and preserved ejection fraction (EF) in a prospective observational study (ARTEMIS study). MethodsIn 834 DM2 patients and 1112 nondiabetic patients with CAD enrolled, the EF measured ≥3 months after qualifying was 63% ± 10% in DM2 patients and 65% ± 8% in nondiabetic patients (P?
机译:BackgroundPrevious研究表明2型糖尿病(DM2)与心脏性猝死死亡(SCD) post-myocardial梗塞的风险病人。疾病(CAD)以及DM2改变了过去时间。比较SCD, DM2的发病率非糖尿病的患者CAD和保留射血分数(EF)在未来观察性研究(阿耳特弥斯研究)。834年DM2患者和1112名非糖尿病的患者随着CAD登记,EF测量≥3个月在排位赛DM2患者63%±10%在非糖尿病患者和65%±8%患者(P < ? . 01)。主要终点是SCD或复苏从心脏骤停(SCA)。死亡率、心脏病死亡率、non-SCD、心力衰竭的住院,严重冠脉综合征是次要的结束点。ResultsDuring平均随访6.3±1.6年,SCDs / sca发生在50个病人。高患病率SCD / SCA DM2的病人(4.1%)比非糖尿病的患者(1.4%)(调整后的风险比2.6;区间1.3 - -5.3;P < . 01)。组件的心脏死亡率DM2之间明显不同非糖尿病的患者。在DM2病人住院更常见(8.4%)比非糖尿病的患者(2.9%)(P <措施)。非糖尿病的CAD患者为0.50%,低于0.59%的报道芬兰的人口。在CAD SCD / SCA的独立危险因素保存患者EF。略低于非糖尿病的CAD病人在一般人群在当下治疗时代。

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