Impact of sepsis on risk of postoperative arterial and venous thromboses: large prospective cohort study

摘要

Preoperative sepsis represents a major determinant of postoperative arterial and venous thromboses in almost all surgical settings. This risk is already clinically important in early stages of sepsis without a proved infectious agent and increases with the severity of the inflammatory response. The risk of arterial and venous thromboses should be recognised in preoperative patients with any grade of sepsis. Arterial and venous thromboses represent common serious postoperative complications. This study showed that preoperative sepsis was an important independent risk factor for both arterial and venous thromboses, with about three times the risk of each of these complications compared with patients without evidence of preoperative sepsis.