Steroid-responsive meningitis-arteritis secondary to septic arthritis due to Pasteurella multocida in a bull terrier puppy

摘要

A 3-month-old male, entire, English bull terrier was presented for investigation of a 24-hour history of lethargy, pyrexia and neck pain. Inflammatory cerebrospinal and synovial fluid analyses with identification of Pasteurella multocida in the left stifle were supportive of a steroid-responsive meningitis-arteritis (SRMA) and immune-mediated arthritis secondary to septic arthritis in the left stifle. The patient was successfully treated with amoxicillin/clavulanic acid and immunosuppressive doses of corticosteroids. Follow-up sampling of cerebrospinal and synovial fluids revealed resolution of the septic arthritis and SRMA after 6 weeks of treatment. Medications were tapered and discontinued after 16 weeks of treatment without any signs of relapse. Follow-up was 16 weeks. This is the first case report of SRMA with the identification of P. multocida septic arthritis as the suspected trigger.