An Injectable Self‐Healing Multifluorescent Hydrogel Formed by Engineered Coiled‐Coil Polypeptide and Quantum Dots

摘要

Abstract An injectable and self‐healing multifluorescent hydrogel system based on engineered coiled‐coil polypeptide and CdSe@ZnS quantum dots (QDs) is developed. The mechanical properties of the PC 10 A‐QD hydrogel are able to be tuned by changing the concentrations of PC 10 A and QDs. The G′ of PC 10 A hydrogel increases from 800 to 1000?Pa by doping 6?n m oil‐soluble CdSe@ZnS QDs. The PC 10 A‐QD hydrogel can easily pass through a 26‐gauge needle without clogging. In addition, through interfacial assembly of PC 10 A polypeptide on the surface of the PC 10 A‐QD hydrogel, each of these hydrogel can self‐assemble into a multifluorescent hydrogel. This approach for preparation of injectable self‐healing multifluorescent hydrogels is expected to apply in biomedicine.