首页> 外文期刊>Human fertility: journal of the British Fertility Society >Anti-Mullerian Hormone (AMH) levels in serum and follicular fluid as predictors of ovarian response in stimulated (IVF and ICSI) cycles.
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Anti-Mullerian Hormone (AMH) levels in serum and follicular fluid as predictors of ovarian response in stimulated (IVF and ICSI) cycles.

机译:在血清和她们血液中的抗苗勒氏管激素(抗苗勒氏管激素)水平和预测卵巢的卵泡液反应刺激(IVF和ICSI)周期。

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INTRODUCTION: Anti-Mullerian Hormone (AMH) was recently introduced as a marker of ovarian reserve in assisted reproduction. The cutoff values of AMH for prediction of poor response have not yet been determined. MATERIAL AND METHODS: Ninety women undergoing their first IVF/ICSI cycle were prospectively included in this clinical, non-interventional study. Baseline AMH, follicle stimulating hormone (FSH) and antral follicle count (AFC) were measured before starting ovarian stimulation. AMH was also measured on day 5 of stimulation and in the follicular fluid of the first aspirated follicle. The predictive value of baseline AMH, day 5 AMH and follicular fluid AMH were assessed comparatively to FSH and AFC for ovarian response. Ovarian response was defined as poor (12 oocytes) or normal (>/=4 oocytes and
机译:作品简介:她们血液中的抗苗勒氏管激素(抗苗勒氏管激素)最近推出了卵巢的标志在辅助生殖技术储备。值预测抗苗勒氏管激素的不良反应尚未确定。方法:九十名妇女接受他们的第一个IVF / ICSI前瞻性纳入周期这个临床,non-interventional研究。抗苗勒氏管激素,促卵泡激素(FSH)窦的卵泡计数(AFC)测量卵巢刺激开始。在第五天的刺激和计量第一吸气卵泡卵泡液。基线抗苗勒氏管激素的预测价值,第五天抗苗勒氏管激素和卵泡液抗苗勒氏管激素进行评估相对FSH和亚足联卵巢响应。( 12卵母细胞)或正常(> / = 4卵母细胞和< / = 12卵母细胞)。病人遇到高卵巢的标准因此分析集中在回应预测的反应。不良反应者之间的差异存在和贫困人员FSH (p =0.019),基线抗苗勒氏管激素(p = 0.002),亚足联(p <0.001),第五天抗苗勒氏管激素(p = 0.005),但不是卵泡抗苗勒氏管激素(p = 0.183)。为贫困卵巢反应曲线下)通过亚足联(AUC = 0.81)基线紧随其后抗苗勒氏管激素(AUC = 0.70)。测试的敏感性是69%,特异性为70.5%。几乎一样好可怜的卵巢的预测响应作为亚足联。

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