Multifunctional gold nanocomposites designed for targeted CT/MR/optical trimodal imaging of human non-small cell lung cancer cells

Chen Jingwen; Sun Yingqi; Chen QianWang LeWang SuheTang YunShi XiangyangWang Han

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Multifunctional gold nanocomposites designed for targeted CT/MR/optical trimodal imaging of human non-small cell lung cancer cells

机译：多功能黄金纳米复合材料设计针对CT /先生/三峰光学成像技术的人非小细胞肺癌细胞

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Multifunctional gold nanocomposites, which were designed as dendrimer-entrapped gold nanoparticles functionalized with gadolinium, cyanine dye (Cy5.5), and folic acid, were synthesized to be used as the first dendrimer-based clinical nanoprobes for targeted X-ray computed tomography/magnetic resonance/optical trimodal imaging in vitro and in vivo of human non-small cell cancer cells.

机译：多功能金纳米复合材料,设计为dendrimer-entrapped黄金携带钆的纳米颗粒,花青染料(Cy5.5),和叶酸作为第一个合成dendrimer-based临床nanoprobes目标x射线计算机断层扫描/磁共振/三峰光学成像技术在体外人类非小细胞肿瘤细胞的体内。

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《Nanoscale》 |2016年第28期|13568-13573|共6页
作者
Chen Jingwen; Sun Yingqi; Chen QianWang LeWang SuheTang YunShi XiangyangWang Han;
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作者单位

Donghua Univ, State Key Lab Modificat Chem Fibers & Polymer Mat, Shanghai 201620, Peoples R China;

Shanghai Univ Tradit Chinese Med, Yueyang Hosp, Dept Radiol, Shanghai 200437, Peoples R China;

Shanghai Jiao Tong Univ, Sch Med, Shanghai Gen Hosp, Dept Radiol, Shanghai 200080, Peoples R ChinaUniv Michigan, Michigan Nanotechnol Inst Med & Biol Sci, Ann Arbor, MI 48109 USAFudan Univ, Dept Chem, iChEM Collaborat Innovat Ctr Chem Energy Mat, Shanghai 200433, Peoples R China;

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正文语种英语
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Imaging; Non-Small-Cell Lung Carcinoma; cancer cellNanocompositesNANOPROBECyanine dyesFolic Acid;

机译：成像;非小细胞肺癌;癌症cellNanocompositesNANOPROBECyanine dyesFolic酸;

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机译：Adu; Aged;; Aged, 80 and over;; Antineoplastic Agents;; Carcinoma, Non-Small-Cell Lung;; Cisplatin;; Cohort Studies;; Deoxycytidine;; Female;; Humans;; Lung Neoplasms;; Male;; Middle Aged;; Mitomycin;; Neoadjuvant Therapy;; Neoplasm Staging;; Pneumonectomy;; Retrospective Studies;; Treatment Outcome;; Vinblastine;; *成年人;; 老年人;; 老年人, 80以上;; 抗肿瘤药;; 癌, 非小细胞肺;; 顺铂;; 队列研究;; 脱氧胞苷;; 肺肿瘤;; 肿瘤辅助疗法;; 肿瘤分期;; 肺切除术;; 回顾性研究;; 治疗结果;; 长春碱
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Multifunctional gold nanocomposites designed for targeted CT/MR/optical trimodal imaging of human non-small cell lung cancer cells

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