Study Results from University of Southampton Update Understanding of Environmental Research and Public Health (Environmental Exposures around Conception: Developmental Pathways Leading to Lifetime Disease Risk)

摘要

2021 SEP 23 (NewsRx) - By a News Reporter-Staff News Editor at Disease Prevention Daily - New research on environmental research and public health is the subject of a new report. According to news originating from Southampton, United Kingdom, by NewsRx correspondents, research stated, "Environment around conception can influence the developmental programme with lasting effects on gestational and postnatal phenotype and with consequences for adult health and disease risk." Financial supporters for this research include Biotechnology and Biological Sciences Research Council, UK; Seventh Framework Programme. The news correspondents obtained a quote from the research from University of Southampton: "Peri-conception exposure comprises a crucial part of the 'Developmental Origins of Health and Disease' (DO-HaD) concept. In this review, we consider the effects of maternal undernutrition experienced during the peri-conception period in select human models and in a mouse experimental model of protein restriction. Human datasets indicate that macronutrient deprivation around conception affect the epigenome, with enduring effects on cardiometabolic and neurological health.