New Lung Cancer Findings from Shengjing Hospital of China Medical University Described (Umbrella Review on Associations Between Single Nucleotide Polymorphisms and Lung Cancer Risk)

摘要

2021 SEP 21 (NewsRx) - By a News Reporter-Staff News Editor at Disease Prevention Daily - Investigators publish new report on lung cancer. According to news reporting out of Shenyang, People's Republic of China, by NewsRx editors, research stated, "The aim is to comprehensively and accurately assess potential relationships between single nucleotide polymorphisms (SNP) and lung cancer (LC) risk by summarizing the evidence in systematic reviews and meta-analyses. This umbrella review was registered with the PROSPERO international prospective register of systematic reviews under registration number CRD42020204685." Our news correspondents obtained a quote from the research from Shengjing Hospital of China Medical University: "The PubMed, Web of Science, and Embase databases were searched to identify eligible systematic reviews and meta-analyses from inception to August 14, 2020. The evaluation of cumulative evidence was conducted for associations with nominally statistical significance based on the Venice criteria and false positive report probability (FPRP). This umbrella review finally included 120 articles of a total of 190 SNP. The median number of studies and sample size included in the meta-analyses were five (range, 3-52) and 4 389 (range, 354-256 490), respectively.