Recent Findings from University of Auckland Highlight Research in Diet and Nutrition (The Impact of Maternal High-Fat Diet on Bone Microarchitecture in Offspring)

摘要

2021 SEP 17 (NewsRx) - By a News Reporter-Staff News Editor at Disease Prevention Daily- Investigators discuss new findings in diet and nutrition. According to news reporting out of Auckland, New Zealand, by NewsRx editors, research stated, "The incidence of obesity in women of reproductive age has significantly increased over the past 100 years." Funders for this research include Health Research Council of New Zealand; American Society for Bone and Mineral Research; Auckland Medical Research Foundation; University of Auckland. The news correspondents obtained a quote from the research from University of Auckland: "There is a well-established connection between maternal obesity during pregnancy and an increased risk of developing non-communicable cardiometabolic diseases in her offspring. This mini-review focuses on evidence examining the effect of maternal high-fat diet (HFD) on skeletal development and bone health in later life in offspring. The majority of rodent studies indicate that maternal HFD generally negatively affects both embryonic bone development and bone volume in adult animals. Details surrounding the mechanisms of action that drive changes in the skeleton in offspring remain unclear, although numerous studies suggest that some effects are sex-specific. Human studies in this area are limited but also suggest that HFD during pregnancy may impair bone formation and increase fracture risk during childhood."