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New Melanoma Research from Medical University of Lublin Discussed (Treatment of malignant melanoma - a review of the literature)

机译:新的黑色素瘤研究的医科大学卢布林(治疗恶性黑色素瘤的讨论-文献之回顾)

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摘要

2021 SEP 17(NewsRx)-Bya News Reporter-Staff News Editor at Disease Prevention Daily-Investigators publish new report on melanoma. According to news reporting from Medical University of Lublin by NewsRx journalists, research stated, "Melanoma is caused by genetic mutations in melanocytes, pigment-producing cells found in the skin, eye, inner ear, and soft meninges. Sun exposure, atypical nevi, previous history of melanoma, and the presence of multiple ( 40) common nevi were found to be associated with an increased risk of melanoma detection (OR: 1." The news editors obtained a quote from the research from Medical University of Lublin: "3; 95% Cl: 1. 1-1. 6). Its prevalence is highest among light-skinned populations and in regions of lower latitudes. Significance of family history of melanoma and presence of congenital nevi were excluded. For localized primary melanoma, the dominant prognostic factors for survival are lesion thickness, ulceration, and lymph node involvement Understanding the pathogenesis of melanoma has been crucial in developing new therapeutic approaches. The characterization of oncogenic signaling pathways and interactions has made it possible to identify new targets for clinically effective therapies, such as pathway inhibitors and antibodies to immune checkpoints or the use of phototherapy."
机译:2021年9月17日(NewsRx)由新闻记者新闻在疾病预防Daily-Investigators编辑器发布的新报告在黑色素瘤。卢布林医科大学的报道NewsRx记者,研究指出,“黑色素瘤在黑色素细胞基因突变造成的,色素细胞中发现的皮肤,眼睛,内耳,软脑膜。非典型痣,先前的黑色素瘤的历史,和存在多个(40)常见的痣发现与风险增加有关黑色素瘤检测(或:1。”获得了引用医学的研究卢布林大学:“3;浅肤色之间的患病率最高人口和纬度较低的地区。黑色素瘤和家族史的重要性存在先天性痣被排除在外。本地化的原发性黑色素瘤,占主导地位的生存是损伤的预后因素厚度、溃疡,淋巴结受累黑色素瘤的发病机制的理解在开发新的治疗至关重要方法。使其信号通路和交互可能为临床确定新的目标有效的治疗方法,比如通路抑制剂和抗体免疫检查点或使用光疗。”

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