Hyperglycemia osmotically draws water into the vascular space, decreasing serum sodium concentration. In 1973, Katz theorized that sodium concentration should decrease by 1.6 mmol/L for every 100-mg/dL increase in serum glucose concentration (to convert serum glucose to millirnoles per liter, multiply by 0.0555). More recent calculations suggest coefficients ranging from 1.35 to 2.0.A study in adults found empirical values ranging from 2.4 to 4.0, contrasting with theoretical estimates. We empirically determined the sodium correction factor for hyperglycemia using data from children with diabetic ketoacidosis.
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机译:高血糖osmotically进了水血管的空间,减少血清钠浓度。钠浓度应该减少1.6更易与每100毫克/ L / dL增加血清葡萄糖浓度(将血清葡萄糖millirnoles每升,乘以0.0555)。最近的计算表明系数从1.35到2.0不等。经验值从2.4到4.0,对比与理论预期。经验决定了钠修正使用数据从儿童因素高血糖糖尿病酮症酸中毒。
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