Children's Hospital of Eastern Ontario Research Institute Researchers Release New Data on Cell and Developmental Biology (Zebrafish Cancer Predisposition Models)

摘要

2021 MAY 07 (NewsRx) - By a News Reporter-Staff News Editor at Disease Prevention Daily - Data detailed on cell and developmental biology have been presented. According to news originating from Ottawa, Canada, by NewsRx correspondents, research stated, "Cancer predisposition syndromes are rare, typically monogenic disorders that result from germline mutations that increase the likelihood of developing cancer. Although these disorders are individually rare, resulting cancers collectively represent 5-10% of all malignancies." Our news reporters obtained a quote from the research from Children's Hospital of Eastern Ontario Research Institute: "In addition to a greater incidence of cancer, affected individuals have an earlier tumor onset and are frequently subjected to long-term multi-modal cancer screening protocols for earlier detection and initiation of treatment. In vivo models are needed to better understand tumor-driving mechanisms, tailor patient screening approaches and develop targeted therapies to improve patient care and disease prognosis. The zebrafish (Danio rerio) has emerged as a robust model for cancer research due to its high fecundity, time- and cost-efficient genetic manipulation and real-time high-resolution imaging.