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摘要

Researchers investigated whether a low cost public campaign by local health authorities reduced antibiotic prescribing for outpatients. A non-randomised controlled trial study design was used. The intervention was multifaceted and included posters, brochures, and advertisements on local media, plus a newsletter on local antibiotic resistance targeted at doctors and pharmacists. The campaign focused primarily on the prescription of antibiotics for upper respiratory tract infections. The trial was based in Emilia-Romagna in northern Italy. The provinces of Modena and Parma (about 1150 000 residents) were chosen forimplementation ofthe intervention between November 2011 and February 2012. The provinces where the campaign was not implemented, with no information provided to doctors and pharmacists, formed the control group (about 3 250 000 residents). The primary outcome was the change in prescribing rates of antibiotics for outpatients over five months. The researchers reported that a low cost community based public campaign targeted at residents, combined with a newsletter on local antibiotic resistance for doctors and pharmacists, was associated with a significantly decreased total rate of antibiotic prescribing. However, the campaign did not affect the participants' knowledge and attitudes about antibiotic resistance.
机译:研究人员调查了当地卫生当局的低成本公共运动是否减少了门诊病人的抗生素处方。使用了非随机对照试验研究设计。干预措施是多方面的,包括当地媒体上的海报,小册子和广告,以及针对医生和药剂师的当地抗生素耐药性的新闻通讯。该运动主要集中于针对上呼吸道感染的抗生素处方。该试验位于意大利北部的艾米利亚 - 罗马尼亚州。选择了2011年11月至2012年2月之间的干预措施的摩德纳和帕尔马省(约有115万居民)。未实施该运动的省份,没有提供给医生和药剂师的信息,组成了对照组(约3 250个250 000居民)。主要结果是五个月内门诊患者的处方抗生素开处方率的变化。研究人员报告说,针对居民的低成本社区公共运动,再加上有关医生和药剂师局部抗生素耐药性的新闻通讯,与抗生素处方的总抗生素总率显着降低有关。但是,该运动并不影响参与者对抗生素抗性的知识和态度。

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