Carbohydrates to Cyclitols Using Mn/CrCl3-Mediated Domino Bernet-Vasella Reductive Elimination and NHK Reaction

摘要

A novel, general and efficient approach for the conversion of carbohydrates to cyclitols was developed utilizing Mn/CrCl3 mediated domino Bernet-Vasella reductive elimination of diiodo precursor of a sugar and NHK reaction to produce four, five and six membered cyclitols. And also, the specific reactivity of Mn/ CrCl3 over Zn on diiodo compounds was studied