Pd-Catalyzed C-H/N-H Arylation: One-Pot Synthesis of Indolo[1, 2-f]phenanthridines

摘要

A novel Pd-catalyzed method for the synthesis of indolo[1, 2- f]phenanthridines from 2-bromo-2'-iodo-1,1'-biphenyl and indole derivatives has been reported. The reaction involves direct N-H and C2-H arylation of indole. This Pd-catalyzed double arylation provides a useful route to synthesize indolo[ 1, 2-f]phenanthridine derivatives from simple and readily accessible starting materials.