Scaffold shift of biologically active pyranone carboxamide to pyrazolyl acetamide, which is another biologically important scaffold was achieved through one-pot base catalyzed metal- free intramolecular ring transformation. Out of the two probable mechanistic pathways (Figure 3), substitution at C-4 by hydrazineyl leading to a pyranone intermediate followed by an intramolecular attack of hydrazineyl at C-6 and decarbox- ylation to yield pyrazolyl acetamides was rationalized through LCMS, UV monitoring and computational studies.
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