Cu~Ⅱ Anchored onto the Magnetic Talc: A New Magnetic Nanostructured Catalyst for the One-Pot Gram-Scale Synthesis of 1H-Pyrazolo[1,2-b]phthalazine-5,10-dione Derivatives

摘要

In the present study CuII anchored onto the magnetic talc (γ-Fe2O3/talc/Cu~Ⅱ NPs) was successfully synthesized and charac-terized by FT-IR, XRD, TEM, FE-SEM, EDX, VSM, and ICP-OES techniques. Structural characterizations reveal that the γ-Fe2O3/talc/CuII NPs are superparamagnetic in nature, structured as a composite with average diameter of about 19-31 nm. The prepared nanostructured catalyst efficiently catalyzed the preparation of 1H-pyrazolo[1,2-b] phthalazine-5,10-diones at the gram scale without the use of the toxic organic solvents. The magnetically separable and environmentally friendly nano-structured catalyst remains quite stable during reaction con-ditions and reused for at least five recycle runs.