A Facile L-Proline Catalyzed One-Pot Synthesis of Xanthene and Acridine Based Quinolones via Knoevenagel Condensation Reaction

摘要

A highly efficient, three-component one-pot and L-proline catalyzed Knoevenagel condensation reaction of substituted-2-phenoxyquinoline-3-carbaldehyde, 1,3-cyclohexanedione/dime-done or ammonium acetate is described. These reactions afford unexpected products of xanthene and acridine based quino-lones in ethanol with good yields. All these isolated products are characterised by spectroscopic and analytical data.