Section 5. Medical science: MODERN ASPECTS IN PREDICTING THE CLINICAL COURSE OF CHRONIC HEPATITIS C

摘要

the aim of the study was to evaluate the diagnostic significance of markers of inflammatory activity and fibrosis in the clinical course of chronic HCV infection. The subject of the study were 107 patients with chronic hepatitis C and liver cirrhosis, as well as 80 healthy donors. The revealed changes in the clinical characteristics, biochemical parameters, genotypes of the virus C, polymorphism of inflammatory regulators and isoenzymes of cytochrome P450 and their interrelation should be taken into account in predictive diagnosis of the disease and in the development of further tactics of therapeutic measures. The obtained data can serve as an additional factor in assessing the risk of progression of the disease course and liver damage and be taken into account when discussing indications for therapy.