Zn~(2+) Recognition for Pathogenesis of Pick’s Disease via a Luminescent Test Kit

摘要

The pathogenesis of Pick’s disease is feasible by detection of the elevated level of Zn~(2+) in the body fluids. This work aims towards developing a suitable chemosensor towards detection of Zn~(2+) in human urine specimen and inside eukaryotic cell line. Fluorescence 'turn on” in the presence of Zn~(2+) makes the chemosensor suitable for its utility in Pick’s disease diagnosis. Real urine sample analysis together within cell detection of Zn~(2+) was successful which leads towards the design and fabrication of a 'ready-to-use” test kit for Zn~(2+) recognition from human urine specimen.