Copper-Catalyzed Sonogashira-Cross-Coupling of Phenols Using Dichloroimidazolidinedione

摘要

Phenols are considered as an ideal alternative to aryl halides as coupling partners in cross-coupling reactions. In this work a copper-catalyzed Sonogashira cross-coupling of phenols using Dichloroimidazolidinedione (DCID) as new C-O activation agent has been developed for the first time. Substituted phenols and phenyl acetylenes were well-matched with the optimizing reaction conditions.