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Troger’s Base Derived Butterfly Shaped Contorted AIEgens for Dead Bacterial Cell-Imaging

机译:Troger的碱基衍生的蝴蝶形扭曲的Aiegens用于死细菌模拟

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This work describes the design and synthesis of contorted dual emissive luminogen based on Tr?ger’s base scaffold. The underlying principle of our design strategy was to use Tr?ger’s base as the core scaffold and functionalize appropriately to avoid the detrimental π-π stacking responsible for the emission quenching and induce RIR in the aggregated state and there- after investigate their photophysical, electrochemical, and thermal properties. The unique white light emission of the fluorophores in the solid-state together with excellent bio- compatibility, photo, and thermal stabilities provided an opportunity for the application of one of the molecules for bacterial cell imaging. The luminogen was biocompatible and surprisingly possess an ability to selectively stain the dead bacterial cell debris, a unique property that can be exploited for the confirmation of cell lysis.
机译:这项工作描述了基于Tr?ger的基本支架的扭曲双发射发光的设计和合成。 我们设计策略的基本原理是将Tr ger的基础用作核心脚手架,并适当地功能功能,以避免有害的π-π堆积,负责发射淬火并在总体状态下诱导RIR,然后在研究其光学,电化学之后 和热性能。 固态中荧光团的独特白光发射以及出色的生物兼容性,照片和热稳定性为应用一种分子进行细菌细胞成像提供了机会。 该腔植物具有生物相容性,令人惊讶的是具有选择性染色的死细菌细胞碎片的能力,这是一种独特的特性,可以利用用于确认细胞裂解的能力。

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