Catalyst-Free Synthesis of Thioethers through C-N Bond Cleavage of Aminonaphthol/Aminophenol Derivatives

摘要

Readily available aminonaphthol/aminophenol derivatives were converted to the corresponding thioethers under catalyst-free reaction conditions.Environmentally benign aqueous medium was utilized for the transformation of aminonaphthol derivatives to the corresponding thioethers under aerobic reaction conditions.Saturated brine solution was identified as a suitable medium for the synthesis of thioethers from aminophenol derivatives.Control experiments revealed that the nature of leaving group and reaction atmosphere plays a vital role in determining the yield of the products.