A NIR-light-driven Black Phosphorus Based Nanocomposite for Combating Bacteria

摘要

Nanocomposites of semiconducting two-dimensional(2D)materials provide advantageous for combating bacterial infections to overcome antibiotic resistance.In this study,the nanocomposites of 2D black phoshorus(BP)and silver nanoparticles(NPs)were prepared by anchoring as-synthesized Ag NPs on few-layer BP nanosheets via liquid self-assembly method and used as a NIR-light-driven antibacterial agent against Gram-negative bacteria(Escherichia coli and Pseudomonas aeruginosa),and Gram-positive bacteria(Enterococcus faecalis and Bacillus cereus).The BP/Ag nanocomposites showed excellent photothermal effect and oxidative stress ability to inhibit the initial logarithmic growth phase of E.faecalis and B.cereus.According to the bacterial growth curve,agar plate assay and live/dead viability test,as-synthesized BP/Ag nanocomposites were found to be more effective antibacterial agent for Gram-positive bacteria than Gram-negative bacteria.The presented NIR-light-driven BP-based nanoplatform can open a new avenue for avoiding bacterial resistance and combating pathogenic bacteria and also broad-spectrum disinfection applications.