Dynamic characteristics of a flagellar motor protein analyzed using an elastic network model

摘要

Graphical abstractDisplay OmittedHighlights?Dynamic characteristics of cytoplasmic ring are investigated using normal mode analysis based on elastic network model.?Transition of FliG protein from wild type to CW-biased provides insights into the structural change switching event.?Structural dynamics of motor protein implies that the reorientation of important domains makes rotation of motor effective.AbstractAt the base of a flagellar motor, its rotational direction and speed are regulated by the interaction between rotor and stator proteins. A switching event occurs when the cytoplasmic rotor protein, called C-ring, changes its conformation in response to binding of the CheY signal protein. The C-ring st