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Outcomes in Super Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy

机译:经历腹腔镜套胃切除术的超级肥胖患者的结果

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Background: Super obese patients remain a challenge for management because of large liver size resulting in decreased work space and associated comorbidities. Objectives: To study outcomes in super obese patients undergoing Laparoscopic sleeve gastrectomy (LSG). Methods: Retrospective data of 123 patients undergoing LSG from January 2008 to March 2015 were analyzed prospectively. Results: Mean age and body mass index (BMI) of 123 patients (± 2 standard deviation [SD]) were 39.9 ± 23.3 years and 55.6 ± 10.54 kg/m~(2), respectively. Mean percentage excess weight loss (%EWL) (± 2 SD) at 1, 3, 5, and 7 years was 63% ± 36.7%, 62.3% ± 29.0%, 56.5% ± 35.8%, and 58.6% ± 40.3%, respectively. The preoperative BMI correlated with %EWL at 1 year ( r ~(2) = 0.0397, P = .044). Staple line leak, bleeding, deep venous thrombosis, and 30-day mortality occurred in 1.6%, 0%, 0.8%, and 0% of the patients, respectively. Stricture formation and new onset gastroesophageal reflux disease (GERD) occurred in 0.8% patients each. Of the diabetic patients, 72.2% had remission and the rest required decreased dosage of oral hypoglycemic medications. Hypertension, obstructive sleep apnea, and GERD improved in 68.2%, 100%, and 25% of the patients, respectively. However, 25% of patients had worsening in GERD symptoms. Conclusions: Super obese patients undergoing LSG as the primary procedure have reasonable weight loss of 62% and 56% at 3 and 5 years, respectively, with significant resolution of comorbidities.
机译:背景:由于肝脏体积过大导致工作空间减少和相关的共病,超肥胖患者仍然是管理的一个挑战。目的:研究腹腔镜袖状胃切除术(LSG)治疗超肥胖患者的疗效。方法:回顾性分析2008年1月至2015年3月123例LSG患者的临床资料。结果:123例患者的平均年龄和体重指数(±2标准差[SD])分别为39.9±23.3岁和55.6±10.54 kg/m2。第1年、第3年、第5年和第7年的平均超重率分别为63%±36.7%、62.3%±29.0%、56.5%±35.8%和58.6%±40.3%。术前BMI与1年时的EWL百分比相关(r~(2)=0.0397,P=0.044)。分别有1.6%、0%、0.8%和0%的患者出现缝合线渗漏、出血、深静脉血栓形成和30天死亡率。狭窄形成和新发胃食管反流病(GERD)各占0.8%。在糖尿病患者中,72.2%的患者病情缓解,其余患者需要减少口服降糖药物的剂量。高血压、阻塞性睡眠呼吸暂停和GERD的改善率分别为68.2%、100%和25%。然而,25%的患者GERD症状恶化。结论:以LSG为主要治疗手段的超肥胖患者在3年和5年时体重分别合理减轻62%和56%,并显著改善了共病。

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