Prognostic impact of geriatric assessment in elderly patients with non-small cell lung cancer: an integrated analysis of two randomized phase III trials (JCOG1115-A)

Katayama Hiroshi; Mizusawa Junki; Fukuda Haruhiko; Nakamura Shinichiro; Nakamura Kenich; Saijo Nagahiro; Yokoyama Akira; Ohe Yuichro; Shinkai Tetsu; Nakagawa Kazuhiko; Abe Tetsuya; Mitsuoka Shigeki; Okamoto Hiroaki; Yamamoto Nobuyuki; Yoshioka Hiroshige; Ando Masahiko; Tamura Tomohide; Takeda Koji

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Prognostic impact of geriatric assessment in elderly patients with non-small cell lung cancer: an integrated analysis of two randomized phase III trials (JCOG1115-A)

机译：老年非小细胞肺癌老年患者对老年患者的预后影响：两项随机三期试验的综合分析（JCOG1115-A）

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摘要

Objective: Patients' actual age and performance status do not always accurately identify the 'fit elderly' for chemotherapy. This study aimed to determine whether four geriatric assessment tools could predict prognosis.

机译：目的：患者的实际年龄和工作状态并不总是能准确地确定适合化疗的“适合老年人”。本研究旨在确定四种老年评估工具是否可以预测预后。

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来源
《Japanese journal of clinical oncology.》 |2021年第5期|共8页
作者
Katayama Hiroshi; Mizusawa Junki; Fukuda Haruhiko; Nakamura Shinichiro; Nakamura Kenich; Saijo Nagahiro; Yokoyama Akira; Ohe Yuichro; Shinkai Tetsu; Nakagawa Kazuhiko; Abe Tetsuya; Mitsuoka Shigeki; Okamoto Hiroaki; Yamamoto Nobuyuki; Yoshioka Hiroshige; Ando Masahiko; Tamura Tomohide; Takeda Koji;
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作者单位

Natl Canc Ctr Japan Clin Oncol Grp Data Ctr Operat Off Tokyo Japan;

Natl Canc Ctr Japan Clin Oncol Grp Data Ctr Operat Off Tokyo Japan;

Natl Canc Ctr Japan Clin Oncol Grp Data Ctr Operat Off Tokyo Japan;

West Japan Oncol Grp Data Ctr Osaka Japan;

Natl Canc Ctr Japan Clin Oncol Grp Data Ctr Operat Off Tokyo Japan;

Kindai Univ Fac Med Dept Med Oncol Osaka Japan;

Niigata Canc Ctr Hosp Dept Internal Med Niigata Japan;

Natl Canc Ctr Dept Thorac Oncol Tokyo Japan;

Natl Hosp Org Shikoku Canc Ctr Dept Med &

Thorac Oncol Matsuyama Ehime Japan;

Kindai Univ Fac Med Dept Med Oncol Osaka Japan;

Niigata City Gen Hosp Dept Resp Med Niigata Japan;

Osaka City Univ Grad Sch Med Dept Clin Oncol Osaka Japan;

Yokohama Municipal Citizens Hosp Dept Resp Med Yokohama Kanagawa Japan;

Wakayama Med Univ Hosp Internal Med 3 Wakayama Japan;

Kansai Med Univ Hosp Dept Thorac Oncol Hirakata Osaka Japan;

Nagoya Univ Hosp Dept Adv Med Nagoya Aichi Japan;

St Lukes Int Hosp Thorac Ctr Tokyo Japan;

Osaka City Gen Hosp Dept Med Oncol Osaka Japan;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
geriatric assessment; Mini-Mental State Examination; prognostic factor; non-small cell lung cancer;

机译：老年评估;迷你精神状态检查;预后因素;非小细胞肺癌;

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1. Shenfu injection plus vinorelbine for elderly patients with non-small cell lung cancer in promoting the quality of life： a randomized controlled clinical trial [J] . Yan Hu, Anji Hou, Hongwei Zhang, 中德临床肿瘤学杂志：英文版 . 2010,第001期
2. Equivalent efficacy study of QL1101 and bevacizumab on untreated advanced non-squamous non-small cell lung cancer patients: a phase 3 randomized, double-blind clinical trial [J] . Tianqing Chu, Qisen Guo, Quan Liu, 癌症生物学与医学（英文版） . 2021,第003期
3. Equivalent efficacy study of QL1101 and bevacizumab on untreated advanced non-squamous non-small cell lung cancer patients: a phase 3 randomized, double-blind clinical trial [J] . Tianqing Chu, Jun Lu, Minghong Bi, 癌症生物学与医学：英文版 . 2021,第003期
4. Prognostic model of survival outcomes in non-small cell lung cancer patients initiated on afatinib: pooled analysis of clinical trial data [J] . Ashley M. Hopkins, Adel Shahnam, Sasha Zhang, 癌症生物学与医学（英文版） . 2019,第002期
5. Prognostic model of survival outcomes in non-small cell lung cancer patients initiated on afatinib: pooled analysis of clinical trial data [J] . Ashley M. Hopkins, Adel Shahnam, Sasha Zhang, 癌症生物学与医学：英文版 . 2019,第002期
6. Prognostic role of a comprehensive geriatric assessment on the management of elderly patients with advanced non-small cell lung cancer (NSCLC): a pooled analysis of two prospective phase II trials by the GFPC Group [J] . Hervé Le Caer, Isabelle Borget, Romain Corre, Journal of Thoracic Disease . 2017,第10期

机译：全面的老年医学评估对老年晚期非小细胞肺癌（NSCLC）患者的管理的预后作用：GFPC集团对两项前瞻性II期试验的汇总分析
7. Docetaxel plus gemcitabine versus gemcitabine in elderly patients with advanced non-small cell lung cancer and use of a geriatric assessment: Lessons from a prematurely closed Hellenic Oncology Research Group randomized phase III study [J] . Athanasios Karampeazis, Lambros Vamvakas, Athanasios Kotsakis, Journal of geriatric oncology . 2017,第1期

机译：Docetaxel Plus Gemcitabine对老年人晚期非小细胞肺癌患者的Gemcitabine和使用大疗法评估：从过早的Hellenic肿瘤学研究组随机化第三阶段研究
8. 21LBA Assessing the value of preoperative chemotherapy in early-stage non-small cell lung cancer: mature data and prognostic factors analysis of a Phase III randomized trial of surgery alone vs preoperative Paclitaxel/Carboplatin (PC) vs postoperative PC. Final NATCH data. A Spanish Lung Cancer Group Trial [J] . B.Massuti, J.M.Sanchez, G.Alonso, European Journal of Cancer Supplements . 2009,第3期

机译：21LBA评估术前早期非小细胞肺癌化疗的价值：一项单独的手术，术前紫杉醇/卡铂（PC）与术后PC的III期随机试验的成熟数据和预后因素分析。最终的NATCH数据。西班牙肺癌小组审判
9. FDG uptake as a biological prognostic factor for recurrence in patients with surgically resected stage Ⅰ non-small cell lung cancer [C] . (missing) China-Japan-Korea conference of nuclear medicine . 2002

机译：FDG吸收作为手术切除阶段Ⅰ非小细胞肺癌患者复发的生物预后因素
10. Predictive Biomarkers of the Efficacy of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Treating Advanced Non-small Cell Lung Cancer: A Systematic Review of Randomized Controlled Trials [D] . Yang, Zuyao. 2014

机译：表皮生长因子受体酪氨酸激酶抑制剂治疗晚期非小细胞肺癌疗效的预测生物标志物：随机对照试验的系统评价。
11. Prognostic role of a comprehensive geriatric assessment on the management of elderly patients with advanced non-small cell lung cancer (NSCLC): a pooled analysis of two prospective phase II trials by the GFPC Group [O] . Hervé Le Caer, Isabelle Borget, Romain Corre, 2017

机译：全面的老年医学评估对老年晚期非小细胞肺癌（NSCLC）患者的管理的预后作用：GFPC集团对两项前瞻性II期试验的汇总分析
12. P2-239: A randomized phase III study of carboplatin-gemcitabine (CG) versus carboplatin-paclitaxel (CP) in elderly patients (pts) with advanced non-small cell lung cancer (NSCLC) with emphasis on geriatric assessment and quality of life (QoL): The NVALT-3 study [O] . Biesma Bonne, Wymenga Machteld N., Vincent Andrew, 2007

机译：P2-239：卡铂-吉西他滨（CG）与卡铂-紫杉醇（CP）在晚期非小细胞肺癌（NSCLC）的老年患者中的随机III期研究，重点是老年病评估和生活质量（（QoL）：NVALT-3研究
13. Phase 1 Trial of an Immune Checkpoint Inhibitor plus Stereotactic Ablative Radiotherapy in Patients with Inoperable Stage I Non-Small Cell Lung Cancer. [R] . Kelly, K., Monjazeb, A., Daly, M., 2017

机译：免疫检查点抑制剂加立体定向消融放疗治疗不能手术的I期非小细胞肺癌的1期试验。

Prognostic impact of geriatric assessment in elderly patients with non-small cell lung cancer: an integrated analysis of two randomized phase III trials (JCOG1115-A)

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