BIOMIMETIC SYNTHESIS OF IHEYAMINE A FROM SPIROCYCLIC OXINDOLES

摘要

The biomimetic synthesis of azepinobisindole alkaloid iheyamine A from a spirocyclic oxindole via an oxidative rearrangement has been accomplished for the first time. Furthermore, an unprecedented method for constructing 2,1'-spirocyclic oxindoles from azepinobisindoles through an alternative oxidative rearrangement has been explored.