SYNTHESIS AND CYTOTOXICITY OF NOVEL BIS-ELLIPTICINES AND BIS-ISOELLIPTICINES

Obaza-Nutaitis Judy A.; Gribble Gordon W.

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SYNTHESIS AND CYTOTOXICITY OF NOVEL BIS-ELLIPTICINES AND BIS-ISOELLIPTICINES

机译：新型双椭圆髓和双肌腱的合成和细胞毒性

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A series of bis-ellipticines 7-9 and bis-isoellipticines 10-12 tethered through the indole nitrogen was synthesized and screened for antitumor cytotoxicity in the L-1210 murine leukemia assay. Activity was only displayed by 1,10-bis(6-ellipticinyl)-n-decane (8).

机译：合成了一系列通过吲哚氮栓系的双椭圆肽7-9和双等椭圆肽10-12，并在L-1210小鼠白血病试验中筛选其抗肿瘤细胞毒性。活性仅由1,10-二（6-椭圆酰）-正癸烷（8）显示。

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来源
《Heterocycles: An International Journal for Reviews and Communications in Heterocyclic Chemistry 》 |2019年第1期| 共17页
作者
Obaza-Nutaitis Judy A.; Gribble Gordon W.;
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Dartmouth Coll Dept Chem Hanover NH 03755 USA;

Dartmouth Coll Dept Chem Hanover NH 03755 USA;

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正文语种 eng
中图分类化学 ;
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SYNTHESIS AND CYTOTOXICITY OF NOVEL BIS-ELLIPTICINES AND BIS-ISOELLIPTICINES

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