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An Eastern Association for the Surgery of Trauma multicenter trial examining prehospital procedures in penetrating trauma patients

机译:东方协会术后创伤多中心试验检查渗透创伤患者的前孢子手术

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摘要

BACKGROUND Prehospital procedures (PHP) by emergency medical services (EMS) are performed regularly in penetrating trauma patients despite previous studies demonstrating no benefit. We sought to examine the influence of PHPs on outcomes in penetrating trauma patients in urban locations where transport to trauma center is not prolonged. We hypothesized that patients without PHPs would have better outcomes than those undergoing PHP. METHODS This was an Eastern Association for the Surgery of Trauma-sponsored, multicenter, prospective, observational trial of adults (18+ years) with penetrating trauma to the torso and/or proximal extremity presenting at 25 urban trauma centers. The impact of PHPs and transport mechanism on in-hospital mortality were examined. RESULTS Of 2,284 patients included, 1,386 (60.7%) underwent PHP. The patients were primarily Black (n = 1,527, 66.9%) males (n = 1,986, 87.5%) injured by gunshot wound (n = 1,510, 66.0%) with 34.1% (n = 726) having New Injury Severity Score of >= 16. A total of 1,427 patients (62.5%) were transported by Advanced Life Support EMS, 17.2% (n = 392) by private vehicle, 13.7% (n = 312) by police, and 6.7% (n = 153) by Basic Life Support EMS. Of the PHP patients, 69.1% received PHP on scene, 59.9% received PHP in route, and 29.0% received PHP both on scene and in route. Initial scene vitals differed between groups, but initial emergency department vitals did not. Receipt of >= 1 PHP increased mortality odds (odds ratio [OR], 1.36; 95% confidence interval [CI], 1.01-1.83; p = 0.04). Logistic regression showed increased mortality with each PHP, whether on scene or during transport. Subset analysis of specific PHP revealed that intubation (OR, 10.76; 95% CI, 4.02-28.78; p < 0.001), C-spine immobilization (OR, 5.80; 95% CI, 1.85-18.26; p < 0.01), and pleural decompression (OR, 3.70; 95% CI, 1.33-10.28; p = 0.01) had the highest odds of mortality after adjusting for multiple variables. CONCLUSION Prehospital procedures in penetrating trauma patients impart no survival advantage and may be harmful in urban settings, even when performed during transport. Therefore, PHP should be forgone in lieu of immediate transport to improve patient outcomes.
机译:背景紧急医疗服务(EMS)定期对穿透性创伤患者实施院前程序(PHP),尽管之前的研究表明没有任何益处。我们试图研究PHPs对城市地区穿透性创伤患者预后的影响,这些地区的创伤中心交通不会延长。我们假设没有PHPs的患者比接受PHP的患者有更好的结果。方法这是一项由东部创伤外科协会赞助的多中心前瞻性观察性试验,对象是25个城市创伤中心的躯干和/或近端穿透性创伤成人(18岁以上)。研究了PHPs和转运机制对住院死亡率的影响。结果2284例患者中,1386例(60.7%)接受了PHP治疗。这些患者主要是黑人(n=1527,66.9%),男性(n=1986,87.5%)因枪伤受伤(n=1510,66.0%),其中34.1%(n=726)的新损伤严重程度评分大于等于16。共有1427名患者(62.5%)通过高级生命支持EMS运送,17.2%(n=392)通过私家车运送,13.7%(n=312)通过警察运送,6.7%(n=153)通过基本生命支持EMS运送。在PHP患者中,69.1%在现场接受PHP,59.9%在途中接受PHP,29.0%在现场和途中接受PHP。两组的初始现场生命体征不同,但急诊室的初始生命体征没有差异。接受>=1 PHP的患者死亡率优势增加(优势比[OR],1.36;95%置信区间[CI],1.01-1.83;p=0.04)。逻辑回归显示,无论是在现场还是在运输过程中,每种PHP的死亡率都会增加。特定PHP的子集分析显示,经多变量调整后,插管(OR,10.76;95%CI,4.02-28.78;p<0.001)、C型脊柱固定(OR,5.80;95%CI,1.85-18.26;p<0.01)和胸膜减压(OR,3.70;95%CI,1.33-10.28;p=0.01)的死亡率最高。结论穿透性创伤患者的院前手术没有带来生存优势,在城市环境中,即使在运输过程中进行,也可能有害。因此,为了改善患者的预后,应该放弃PHP而不是立即运送。

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  • 作者单位

    Tulane Univ Sch Med Dept Surg Div Trauma &

    Crit Care New Orleans LA 70112 USA;

    Temple Univ Div Trauma &

    Acute Care Surg Dept Surg Philadelphia PA 19122 USA;

    Temple Univ Div Trauma &

    Acute Care Surg Dept Surg Philadelphia PA 19122 USA;

    Mt Sinai Hosp Dept Surg New York NY 10029 USA;

    Mt Sinai Hosp Dept Surg New York NY 10029 USA;

    Tulane Univ Sch Med Dept Surg Div Trauma &

    Crit Care New Orleans LA 70112 USA;

    Tulane Univ Sch Med Dept Surg Div Trauma &

    Crit Care New Orleans LA 70112 USA;

    Cook Cty Hlth Dept Trauma &

    Burn Chicago IL USA;

    Cook Cty Hlth Dept Trauma &

    Burn Chicago IL USA;

    Univ Penn Dept Surg Div Traumatol Surg Crit Care &

    Emergency Surg Philadelphia PA 19104 USA;

    Univ Penn Dept Surg Div Traumatol Surg Crit Care &

    Emergency Surg Philadelphia PA 19104 USA;

    Loma Linda Univ Med Ctr Dept Surg Loma Linda CA USA;

    Loma Linda Univ Med Ctr Dept Surg Loma Linda CA USA;

    Univ Calif Davis Div Trauma Acute Care Surg &

    Surg Crit Care Dept Surg Med Ctr Sacramento CA;

    Univ Calif Davis Div Trauma Acute Care Surg &

    Surg Crit Care Dept Surg Med Ctr Sacramento CA;

    Cooper Univ Hosp Dept Surg Camden NJ USA;

    Cooper Univ Hosp Dept Surg Camden NJ USA;

    Grant Med Ctr Dept Surg Div Trauma &

    Acute Care Surg Columbus OH USA;

    Grant Med Ctr Dept Surg Div Trauma &

    Acute Care Surg Columbus OH USA;

    Our Lady Lake Reg Med Ctr Trauma Specialist Program Baton Rouge LA USA;

    Allegheny Gen Hosp Dept Surg Pittsburgh PA 15212 USA;

    Allegheny Gen Hosp Dept Surg Pittsburgh PA 15212 USA;

    Cape Fear Valley Hosp Dept Surg Fayetteville NC USA;

    Ascens St Vincent Hosp Trauma Adm Indianapolis IN USA;

    Ascens St Vincent Hosp Trauma Adm Indianapolis IN USA;

    Univ Rochester Med Ctr Dept Surg Div Acute Care Surg &

    Trauma Rochester NY 14642 USA;

    Univ Rochester Med Ctr Dept Surg Div Acute Care Surg &

    Trauma Rochester NY 14642 USA;

    Sydney &

    Lois Eskenazi Hosp Smith Level I Shock T Dept Surg Div Acute Care Surg Indianapolis IN;

    Sydney &

    Lois Eskenazi Hosp Smith Level I Shock T Dept Surg Div Acute Care Surg Indianapolis IN;

    Res Med Ctr Dept Surg Kansas City MO USA;

    Broward Hlth Med Ctr Div Trauma Crit Care Ft Lauderdale FL USA;

    Broward Hlth Med Ctr Div Trauma Crit Care Ft Lauderdale FL USA;

    Brigham &

    Womens Hosp Dept Surg Div Trauma Burn Surg Crit Care &

    Emergency Gen Su 75 Francis St;

    Brigham &

    Womens Hosp Dept Surg Div Trauma Burn Surg Crit Care &

    Emergency Gen Su 75 Francis St;

    Johns Hopkins Univ Sch Med Div Acute Care Surg Dept Surg Baltimore MD USA;

    Johns Hopkins Univ Sch Med Div Acute Care Surg Dept Surg Baltimore MD USA;

    Johns Hopkins Bayview Med Ctr Dept Surg Div Acute Care Surg Baltimore MD 21224 USA;

    Johns Hopkins Bayview Med Ctr Dept Surg Div Acute Care Surg Baltimore MD 21224 USA;

    Univ Kentucky Div Acute Care Surg Dept Surg Lexington KY USA;

    Univ Kentucky Div Acute Care Surg Dept Surg Lexington KY USA;

    Ascens Via Christi Hosp St Francis Trauma Serv Wichita KS USA;

    Ascens Via Christi Hosp St Francis Trauma Serv Wichita KS USA;

    Univ Texas Hlth Tyler Trauma Serv Tyler TX USA;

    Univ Texas Hlth Tyler Trauma Serv Tyler TX USA;

    Med City Plano Envis Surg Serv Plano TX USA;

    Med City Plano Envis Surg Serv Plano TX USA;

    Tufts Med Ctr Dept Surg Div Trauma &

    Acute Care Surg Boston MA 02111 USA;

    Tufts Med Ctr Dept Surg Div Trauma &

    Acute Care Surg Boston MA 02111 USA;

    Tulane Univ Sch Med Dept Surg Div Trauma &

    Crit Care New Orleans LA 70112 USA;

    Our Lady Lake Reg Med Ctr Trauma Specialist Program Baton Rouge LA USA;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 外科学;
  • 关键词

    Penetrating trauma; prehospital procedures; prehospital transport; outcomes;

    机译:穿透创伤;预孢子手术;预孢子运输;结果;

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