Quantitative analysis of ovarian cysts and tumors by using T2 star mapping

摘要

Abstract Aim The aim of this study was to investigate the efficacy of T2 star (T2*) mapping in diagnosing ovarian cysts/ tumors. Methods Pelvic magnetic resonance examinations including T2*WI were performed before surgery in 35 patients. The region of interest, consisted of a 10?mm 2 diameter circle, was set as much as possible inside ovarian tumors/cysts to measure T2*values, and mean T2* values were compared in ovarian cyst/tumor types, retrospectively. Diagnoses of 40 ovarian cysts/tumors were determined by pathological reports, in which 17 were endometriomas, 13 were mature cystic teratomas, 6 were mucinous cystadenomas and 4 were serous cystadenomas. Results The average T2* values of endometrioma was 56.8?±?8.7?ms (mean?±?SEM), which was significantly lower than that of mucinous cystadenoma (334.2?±?58.5?ms, mean?±?SEM) or serous cystadenoma (237.0?±?45.4?ms, mean?±?SEM). There was no difference in T2* values between endometrioma and mature cystic teratoma (64.1?±?22.6?ms, mean?±?SEM). Receiver operating characteristics curve analysis revealed that optimal cut‐off value for differential diagnosis of endometrioma and mucinous or serous cystadenoma was 149.2?ms as T2* value, which has an area under the curve of 0.95 (sensitivity = 92.4%, specificity = 78.6%). Conclusion T2* values were useful to diagnose various types of ovarian cyst/tumor.